We have publications in the following fields of research. Click the topic to get to the subsection you are interested in:

Peer-reviewed Publications
  1. Z. Ji, J. Kozuch, I. I. Mathews, C. S. Diercks, Y. Shamsudin, M. A. Schulz, S. G. Boxer*
    Protein electric fields enable faster and longer-lasting covalent inhibition of beta-lactamases
    J. Am. Chem. Soc., 2022, 144, 20947-20954.
  2. T. Utesch, J. K. Staffa, S. Katz, G. Yao, J. Kozuch,* P. Hildebrandt*
    Potential distribution across model membranes
    J. Phys. Chem. B, 2022. 126, 7664-7675.
  3. C. Zheng, Y. Mao, J. Kozuch, A. Atsango, Z. Ji, T. Markland,* S. G. Boxer*
    Electric field orientations in solution and enzyme active site revealed by a two-dimensional vibrational probe
    Nat. Chem., 2022, 14, 891-897.
  4. J. B. Weaver, J. Kozuch, J. M. Kirsh, S. G. Boxer*
    Nitrile IR intensities characterize electric fields and hydrogen bonding in protic, aprotic, and protein environments
    J. Am. Chem. Soc., 2022, 144, 7562–7567.
  5. M. La Greca, J. L. Chen, L. Schubert, J. Kozuch, T. Berneiser, U. Terpitz, J. Heberle, R. Schlesinger*
    The Photoreaction of the Proton-Pumping Rhodopsin 1 From the Maize Pathogenic Basidiomycete Ustilago maydis
    Front. Mol. Biosci., 2022, 9, 829660.

  6. S. H. Schneider, J. Kozuch, S. G. Boxer*
    The interplay of electrostatics and chemical positioning in the evolution of antibiotic resistance in TEM beta-lactamases
    ACS Cent. Sci., 2021, 7, 1996-2008.
  7. A. Kraskov, J. Von Sass, A. D. Nguyen, T. O. Hoang, D. Buhrke, S. Katz, N. Michael, J. Kozuch, I. Zebger, F. Siebert, P. Scheerer, M. A. Mroginski,* N. Budisa,* P. Hildebrandt,*
    Electric Field Changes during the Photoconversion of the Bathy Phytochrome Agp2
    Biochemistry, 2021, 60, 2967-2977.
  8. J. Kozuch,* S. H. Schneider, C. Zheng, Z. Ji, R. T. Bradshaw, S. G. Boxer*
    Testing the limitations of MD-based local electric fields using the vibrational Stark effect in solution: pencillin G as a test case
    J. Phys. Chem. B, 2021, 125, 4415-4427.
  9. F. Baserga, J. Drageli, J. Kozuch, H. Mohrmann, E.-W. Knapp. S. T. Stripp, J. Heberle*
    Quantification of local electric field changes in the active site of cytochrome c oxidase by FTIR spectroelectrochemical titrations
    Front. Chem., 2021, 9, 669452.

  10. J. Kozuch, S. H. Schneider, S. G. Boxer*
    Biosynthetic incorporation of site-specific isotopes in β-lactam antibiotics enables biophysical studies
    ACS Chem. Bio., 2020, 15, 1148-1153.
  11. U. Szczepaniak, S. H. Schneider, R. Horvath, J. Kozuch, M. Geiser*
    Vibrational Stark spectroscopy of fluorobenzene using quantum cascade laser dual frequency combs
    Appl. Spec., 2020, 74, 347-356.

  12. A. de Miguel Catalina, E. Forbrig, J. Kozuch, C. Nehls, L. Paulowski, T. Gutsmann, P. Hildebrandt,* M. A. Mroginski*
    The C-terminal VPRTES tail of LL-37 influences the mode of attachment to a lipid bilayer and antimicrobial activity
    Biochemistry, 2019, 58, 2447-2464.

  13. M. Caterino, M. Herrmann, A. Merlino, C. Ricciardi, D. Montesarchio, M. A. Mroginski, D. Musumeci, F. Ruffo, L. Paduano, P. Hildebrandt, J. Kozuch,* A. Vergara*
    On the pH-modulated Ru-based pro-drug activation mechanism Inorg. Chem., 2018, 58, 1216-1223.
  14. H. Biava, T. Schreiber, S. Katz, J.-S. Völler, M. Stolarski, C. Schulz, N. Michael, N. Budisa, J. Kozuch,* T. Utesch,* P. Hildebrandt*
    Long-range modulations of the electric fields in proteins
    J. Phys. Chem. B, 2018, 122, 8330-8342.
  15. T. G. G. A. Harris, N. Heidary, J. Kozuch, S. Frielingsdorf, O. Lenz, M. A. Mroginski, P. Hildebrandt, I. Zebger,* A. Fischer*
    In situ spectroelectrochemical studies into the formation and stability of robust diazoniumderived interfaces on gold electrodes for the immobilization of an oxygen-tolerant hydrogenase
    ACS Appl. Mater. Interfaces, 2018, 10, 23380-23391.
  16. O. Gutierrez-Sanz, E. Forbrig, A. P. Batista, M. I. Pereira, J. Salewski, M. A. Mroginski, R. Götz, A. L. De Lacey, J. Kozuch,* I. Zebger*
    Catalytic activity and proton translocation of reconstituted respiratory complex I monitored by surface-enhanced infrared absorption spectroscopy
    Langmuir, 2018, 34, 57023-5711.
  17. P. Kielb, M. Horch, P. Wrzolek, R. Götz, H. K. Ly, J. Kozuch, M. Schwalbe, I. Weidinger*
    Hydrogen Evolution by cobalt hangman porphyrins under operating conditions studied by vibrational spectro-electrochemistry
    Catal. Sci. Technol., 2018, 8, 1849-1857.
  18. E. Forbrig, J. K. Staffa, J. Salewski, M. A. Mroginski, P. Hildebrandt, J. Kozuch*
    Monitoring the orientational changes of alamethicin during incorporation in bilayer lipid membranes
    Langmuir, 2018, 34, 2373-2385.

  19. J. K. Staffa, L. Lorenz, M. Stolarski, D. H. Murgida, I. Zebger, T. Utesch, J. Kozuch,* P. Hildebrandt*
    Determination of the local electric field at Au/SAM interfaces using the vibrational Stark effect
    J. Phys. Chem. C, 2017, 121, 22274-22285.
  20. P. Kielb, T. Utesch, J. Kozuch, J.-H. Jeoung, H. Dobbek, M. A. Mroginski, P. Hildebrandt, I. Weidinger*
    Switchable redox chemistry of the hexameric tyrosine-coordinated heme protein
    J. Phys. Chem. B, 2017, 121, 3955-3964.

  21. S. Wiebalck, J. Kozuch,* C. C. Tzschucke, L. J. C. Jeuken, P. Hildebrandt*
    Monitoring the transmembrane proton gradient generated by cytochrome bo3 in tethered bilayer lipid membranes using SEIRA spectroscopy
    J. Phys. Chem. B, 2016, 120, 22492256.

  22. H. K. Ly, P. Wrzolek, N. Heidary, R. Götz, M. Horch, J. Kozuch, M. Schwalbe,* I. Weidinger*
    2nd coordination sphere controlled electron transfer of iron hangman complexes on rlectrodes probed by surface-enhanced vibrational spectroscopy
    Chem. Sci., 2015, 6, 6999-7007.
  23. J. Kozuch,* N. Petrusch, D. Gkogkou, U. Gernert, I. M. Weidinger*
    Calculating average surface-enhancement factors of randomly nanostructured electrodes by a combination of SERS and impedance Spectroscopy
    Phys. Chem. Chem. Phys., 2015, 17, 21220-21225.

  24. J. Kozuch,* C. Weichbrodt, D. Millo, K. Giller, S. Becker, P. Hildebrandt,* C. Steinem Voltage-dependent structural changes of the membrane-bound anion channel hVDAC1 probed by SEIRA and electrochemical impedance spectroscopy
    Phys. Chem. Chem. Phys., 2014, 16, 9546-9555.

  25. X. X. Han, C. Köhler, J. Kozuch, U. Kuhlmann, L. Paasche, A. Sivanesan, I. M. Weidinger, P. Hildebrandt*
    Potential-Dependent surface-enhanced resonance Raman spectroscopy at nanostructured TiO2: a case study on cytochrome b5
    Small, 2013, 9, 4175-4181.
  26. J. Kozuch, I. von der Hocht, F. Hilbers, H. Michel, I. M. Weidinger*
    Resonance Raman Characterization of the ammonia-generated intermediate of cytochrome c oxidase from Paracoccus denitrificans.
    Biochemistry, 2013, 52, 6197-6202.

  27. J. Kozuch, C. Steinem, P. Hildebrandt,* D. Millo*
    Combined electrochemistry and surface-enhanced infrared absorption spectroscopy of gramicidin A incorporated into tethered bilayer lipid membranes
    Angew. Chem. Int. Ed., 2012, 51, 8114-8117.
  28. A. Sivanesan, J. Kozuch, H. K. Ly, G. Kalaivani, A. Fischer, I. M. Weidinger*
    Tailored silica coated Ag nanoparticles for non-invasive surface enhanced Raman spectroscopy of biomolecular targets
    RSC Adv., 2012, 2, 805-808.

  29. A. Sivanesan, H. K. Ly, J. Kozuch, M. Sezer, U. Kuhlmann, A. Fischer, I. M. Weidinger*
    Functionalized Ag nanoparticles with tunable optical properties for selective protein analysis
    Chem. Commun., 2011, 47, 3553-3555.