Advanced Vibrational Bio-Nanospectroscopy
As of October 2025, the Kozuch Lab is relocating to the Institute of Physical Chemistry and Theoretical Chemistry, and the BRICS Braunschweig Integrated Centre for Systems Biology at the Technische Universität Braunschweig. Feel free to visit our new group page.
We are using surface-sensitive and nanoscale vibrational spectroscopic methods and vibrational Stark effect spectroscopy to understand how electrostatic interactions sculpt structural and functional motifs in chemistry and biology. Using this approach we are exploring phenomena like electrostatic catalysis, the function of ion channels, and molecular interactions at (bio)interfaces.
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‘In Situ Spectroscopic Detection of Large-Scale Reorientations of Transmembrane Helices During Influenza A M2 Channel Opening’ published in Angew. Chem.
Viroporins are viral ion channels that play important role during viral infection and, thus, present important drug targets. Using SEIRA spectroscopy we monitor the activity of Influenza A M2 proton channel in a model membrane…
Keep readingReview on ‘Surface-enhanced Infrared Absorption Spectroscopy’ in Nat. Rev. Methods Primers
As part of an invitation by Nature Reviews Methods Primers we have published together with Ken Ataka and Joachim Heberle a review on the method of ‘Surface-enhanced Infrared Absorption Spectroscopy’, SEIRAS. SEIRAS enhanced IR spectra…
Keep readingOpen PhD position in Experimental Molecular Biophysics of Protein Misfolding in Neurodegenerative Diseases
PhD position (m/f/d) in Experimental Molecular Biophysics of protein folding and misfolding in neurodegenerative diseases at the Freie Universität Berlin (65% TV-L E13, 36 month) We are again looking for a motivated student who is…
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